Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.59 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.59 |
| ▸ | CLK1 | P49759 | 2/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.56 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29171652 | 0.86 | CES2 (0.61) | MAPTLMNAHTTHPGDESR1 | |
| SCHEMBL10600776 | 0.80 | HSD17B1 (0.59) | MAPTLMNAHTTHPGDESR1 | |
| SCHEMBL9756786 | 0.79 | MAPT (0.66) | MAPTLMNAHTTHPGDSRD5A2 | |
| SCHEMBL9147489 | 0.79 | NPC1 (0.53) | MAPTLMNAHPGDMAPK1RAB9A | |
| SCHEMBL699850 | 0.79 | LMNA (1.00) | MAPTLMNAHTTHPGDESR1 | |
| SCHEMBL18423 | 0.79 | LMNA (1.00) | MAPTLMNAHTTHPGDESR1 | |
| SCHEMBL6495865 | 0.78 | KMT2A (0.66) | MAPTLMNAHPGDCLK1DYRK1A | |
| SCHEMBL29056089 | 0.76 | LMNA (0.94) | MAPTLMNAHTTHPGDESR1 | |
| Methane SCHEMBL6378712 | 0.76 | LMNA (0.94) | MAPTLMNAHTTHPGDESR1 | |
| SCHEMBL7929114 | 0.76 | LMNA (0.94) | MAPTLMNAHTTHPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500493-A1 | Novel poly(arylene etherketones) | CIBA-GEIGY AG (CH) | 1992-08-26 | — | — | EP | disclosed |