Tetrahydrofuran

Tetrahydrofuran

SCHEMBL9148484

C1CCOC1.CCCC(O)O.CCOC(C)OCC

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7722140 0.84 LMNA (0.60) LMNA
Tetrahydrofuran SCHEMBL2260480 0.84 LMNA (0.60) LMNA
Tetrahydrofuran SCHEMBL10986188 0.84 ALDH1A1 (0.40) LMNA
Tetrahydrofuran SCHEMBL9877354 0.84 LMNA (0.60) LMNA
SCHEMBL6867778 0.82 LMNA (0.57) LMNA
SCHEMBL2702135 0.82 LMNA (0.57) LMNA
Tetrahydrofuran SCHEMBL28175157 0.77 ALDH1A1 (0.36) LMNA
Dioxane SCHEMBL7672675 0.76 LMNA (0.67) LMNA
SCHEMBL3945021 0.72 LMNA (0.55) LMNA
SCHEMBL767256 0.72 LMNA (0.55) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113262794-B Supported nickel catalyst, preparation method and application in hydrogenation reaction of 1, 4-butynediol 上海迅凯新材料科技有限公司 2022-12-27 CN disclosed
CN-113262794-A Supported nickel catalyst, preparation method and application in hydrogenation reaction of 1, 4-butynediol 上海迅凯新材料科技有限公司 2021-08-17 CN disclosed
US-5426195-A Process for the catalytic dehydrogenation of diols HUELS AKTIENGESELLSCHAFT (DE) 1995-06-20 US disclosed
US-5110954-A Catalytic conversion to lactone E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-05 US disclosed
WO-1992000973-A1 DEHYDROGENATION OF DIOLS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-23 WO disclosed