Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867778 | 1.00 | LMNA (0.57) | LMNAALDH1A1THRB | |
| Tetrahydrofuran SCHEMBL2260480 | 0.98 | LMNA (0.60) | LMNAALDH1A1THRB | |
| Tetrahydrofuran SCHEMBL9877354 | 0.98 | LMNA (0.60) | LMNAALDH1A1THRB | |
| Dioxane SCHEMBL7672675 | 0.87 | LMNA (0.67) | LMNAALDH1A1THRB | |
| Cyclopropane SCHEMBL1406305 | 0.84 | LMNA (0.80) | LMNATHRB | |
| SCHEMBL7847095 | 0.84 | LMNA (0.80) | LMNATHRB | |
| SCHEMBL767256 | 0.84 | LMNA (0.55) | LMNATHRB | |
| Tetrahydrofuran SCHEMBL9464976 | 0.83 | ALDH1A1 (0.40) | LMNAALDH1A1THRB | |
| Tetrahydrofuran SCHEMBL9148484 | 0.82 | LMNA (0.43) | LMNA | |
| Tetrahydrofuran SCHEMBL10505828 | 0.80 | THRB (0.58) | LMNAALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8884032-B2 | Trioxane monomers and dimers | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-11-11 | — | — | US | disclosed |
| US-20120108545-A1 | Trioxane Monomers and Dimers | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-05-03 | — | — | US | disclosed |
| WO-2010135427-A2 | TRIOXANE MONOMERS AND DIMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108545-A1 | Trioxane Monomers and Dimers | CDK10, TMSB10, CASP10 | LMNA 523/4885ALDH1A1 1853/4885THRB 773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.