Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 13/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004936 | 0.86 | ELANE (0.44) | CA12CA2CA9CA1CA7 | |
| SCHEMBL7247959 | 0.78 | ELANE (0.40) | CA12CA2CA9CA1CA7 | |
| SCHEMBL7290897 | 0.75 | ALDH1A1 (0.46) | CA12CA2CA9CA1CA7 | |
| SCHEMBL9407224 | 0.74 | RET (0.51) | CA12CA2CA9CA1CA7 | |
| SCHEMBL12261822 | 0.74 | CA12 (0.44) | CA12CA2CA9CA1CA7 | |
| SCHEMBL7281545 | 0.73 | ELANE (0.44) | CA12CA2CA9CA1CA7 | |
| SCHEMBL9147890 | 0.73 | ELANE (0.56) | ELANE | |
| SCHEMBL7278719 | 0.70 | CA12 (0.41) | CA12CA2CA9CA1CA7 | |
| SCHEMBL7291109 | 0.70 | CA2 (0.35) | CA12CA2CA9CA1CA7 | |
| SCHEMBL7288589 | 0.69 | ELANE (0.32) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466701-A | Degenerative diseases | STERLING WINTHROP INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5378720-A | Treatment of rheumatoid arthritis, emphysema, pancreatitis | STERLING WINTHROP INC. (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0626378-A1 | Saccharin derivative proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1994-11-30 | — | — | EP | disclosed |