SCHEMBL9149133

SCHEMBL9149133

O=C1c2ccccc2C(=O)c2cc(Oc3ccccc3)c(Oc3ccccc3)cc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.57
HKDC1 Q2TB90 2/20 0.53
NSD2 O96028 1/20 0.53
HSP90AA1 P07900 1/20 0.53
TLR9 Q9NR96 1/20 0.53
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
GAPDH P04406 1/20 0.52
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
CDC25B P30305 1/20 0.50
BCL2 P10415 1/20 0.48
MCL1 Q07820 1/20 0.48
TDP1 Q9NUW8 3/20 0.47
POLB P06746 3/20 0.47
MAPT P10636 3/20 0.47
GSTP1 P09211 1/20 0.47
TTR P02766 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
TP53 P04637 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthraquinone SCHEMBL28596353 0.84 MEN1 (0.63) ADORA2AHKDC1NSD2HSP90AA1TLR9
SCHEMBL12887873 0.82 LTA4H (0.58) KMT2AGSTP1TTRMAPK1TSHR
SCHEMBL2267225 0.82 MAOA (0.62) ADORA2AHKDC1NSD2HSP90AA1TLR9
SCHEMBL10613734 0.80 MAOA (0.61) ADORA2AHKDC1NSD2HSP90AA1TLR9
SCHEMBL1764840 0.79 ADORA2A (0.66) ADORA2AHKDC1NSD2HSP90AA1TLR9
SCHEMBL9130367 0.78 ADORA2A (0.45) ADORA2AHKDC1NSD2HSP90AA1TLR9
SCHEMBL1802680 0.78 NSD2 (0.73) ADORA2AHKDC1NSD2HSP90AA1TLR9
SCHEMBL10932672 0.77 ADORA2A (0.67) ADORA2AHKDC1NSD2HSP90AA1TLR9
SCHEMBL9241413 0.77 ADORA2A (0.55) ADORA2AHKDC1NSD2HSP90AA1TLR9
SCHEMBL10546429 0.76 ADORA2A (0.58) ADORA2AHKDC1NSD2HSP90AA1TLR9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0414251-B1 Thermal transfer image receiving material FUJI PHOTO FILM CO LTD (JP) 1995-01-04 EP disclosed
US-5155090-A Coated with dispersion of fine particles of dye accepting polymer and high boiling organic solvent in water soluble binder FUJI PHOTO FILM CO., LTD. (JP) 1992-10-13 US disclosed
US-5128313-A Thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1992-07-07 US disclosed
US-5102764-A Anthraquinone dye dispersed in polymer particles for developing latent electrostatic images EASTMAN KODAK COMPANY (US) 1992-04-07 US disclosed
EP-0414251-A2 Thermal transfer image receiving material FUJI PHOTO FILM CO., LTD. (JP) 1991-02-27 EP disclosed