Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131037 | 0.82 | MAPT (0.57) | ADORA2AMAPTKMT2APOLBTDP1 | |
| SCHEMBL9133291 | 0.79 | KMT2A (0.53) | ADORA2AMAPTKMT2APOLBTDP1 | |
| SCHEMBL9149133 | 0.78 | ADORA2A (0.57) | ADORA2AMAPTKMT2APOLBTDP1 | |
| SCHEMBL9131759 | 0.78 | MAOA (0.51) | ADORA2AMAPTKMT2APOLBTDP1 | |
| SCHEMBL9130943 | 0.78 | POLB (0.49) | ADORA2AMAPTKMT2APOLBTDP1 | |
| SCHEMBL9297932 | 0.77 | ADORA2A (0.43) | ADORA2AMAPTKMT2APOLBTDP1 | |
| SCHEMBL9132901 | 0.75 | S100A4 (0.51) | ADORA2AMAPTKMT2APOLBTDP1 | |
| SCHEMBL9297216 | 0.75 | MAPT (0.39) | ADORA2AMAPTKMT2APOLBTDP1 | |
| SCHEMBL8510957 | 0.74 | MAPT (0.52) | ADORA2AMAPTKMT2APOLBTDP1 | |
| SCHEMBL9297964 | 0.74 | ADORA2A (0.50) | ADORA2AMAPTKMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407885-A | Photochromic naphthacenequinones, process for their preparation and the use thereof | CIBA-GEIGY CORPORATION (US) | 1995-04-18 | — | — | US | claimed |
| EP-0489689-B1 | Photochromic naphthacenequinones, process for their production and their use | CIBA GEIGY AG (CH) | 1995-03-01 | — | — | EP | claimed |
| US-5208354-A | PHOTOCHROMIC NAPHTHACENEQUINONES, PROCESS FOR THEIR PREPARATION AND THE USE THEREOF | CIBA-GEIGY CORP. (US) | 1993-05-04 | — | — | US | claimed |
| EP-0489689-A1 | Photochromic naphthacenequinones, process for their production and their use | CIBA-GEIGY AG (CH) | 1992-06-10 | — | — | EP | claimed |
| US-5407885-A | Photochromic naphthacenequinones, process for their preparation and the use thereof | CIBA-GEIGY CORPORATION (US) | 1995-04-18 | — | — | US | disclosed |
| EP-0489689-B1 | Photochromic naphthacenequinones, process for their production and their use | CIBA GEIGY AG (CH) | 1995-03-01 | — | — | EP | disclosed |
| US-5208354-A | PHOTOCHROMIC NAPHTHACENEQUINONES, PROCESS FOR THEIR PREPARATION AND THE USE THEREOF | CIBA-GEIGY CORP. (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0489689-A1 | Photochromic naphthacenequinones, process for their production and their use | CIBA-GEIGY AG (CH) | 1992-06-10 | — | — | EP | disclosed |