Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241319 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1MAPTHPGDCYP2C19 | |
| SCHEMBL7933997 | 0.82 | CA1 (0.50) | SMN1; SMN2ALDH1A1MAPTMAPK10LMNA | |
| SCHEMBL10803250 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1MAPTMAPK10LMNA | |
| SCHEMBL9495103 | 0.80 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1MAPTHPGDCYP2C19 | |
| SCHEMBL4243028 | 0.79 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1MAPTHPGDCYP2C19 | |
| SCHEMBL4299155 | 0.78 | TP53 (0.64) | SMN1; SMN2ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL9150227 | 0.78 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1MAPTHPGDCYP2C19 | |
| SCHEMBL7031844 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MAPTMAPK10LMNA | |
| SCHEMBL9148011 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1MAPTHPGDCYP2C19 | |
| SCHEMBL27785864 | 0.75 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1MAPTMAPK10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463100-A | Spraying a mixture of an aminoaryl beta-hydroxyethylsulfone and sulfuric acid into a hot gas stream; drying, esterification and any hydrolysis take place simultaneously; granules | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | claimed |
| EP-0390826-B1 | PROCESS FOR PRODUCING AMINOARYL-BETA-SULPHATOETHYLSULPHONE COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-19 | — | — | EP | claimed |
| US-5463100-A | Spraying a mixture of an aminoaryl beta-hydroxyethylsulfone and sulfuric acid into a hot gas stream; drying, esterification and any hydrolysis take place simultaneously; granules | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |