Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148011 | 0.86 | SMN1; SMN2 (0.49) | ALDH1A1HPGDKDM4CKMT2AKDM4E | |
| SCHEMBL9149244 | 0.78 | SMN1; SMN2 (0.53) | ALDH1A1HPGDKDM4CKMT2AMAPT | |
| SCHEMBL14426553 | 0.74 | HPGD (0.78) | ALDH1A1HPGDKDM4CKMT2AKDM4E | |
| SCHEMBL10658933 | 0.74 | ALDH1A1 (0.73) | ALDH1A1HPGDKDM4CKMT2AKDM4E | |
| SCHEMBL15886354 | 0.74 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4CKMT2AKDM4E | |
| SCHEMBL10802549 | 0.72 | HPGD (0.51) | ALDH1A1HPGDKDM4CKMT2AKDM4E | |
| SCHEMBL14962804 | 0.72 | HPGD (0.81) | ALDH1A1HPGDKDM4CKMT2AKDM4E | |
| SCHEMBL7034776 | 0.71 | MEP1B (0.46) | ALDH1A1HPGDKMT2AL3MBTL1MAPT | |
| SCHEMBL11521917 | 0.69 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4CKMT2AKDM4E | |
| SCHEMBL11236825 | 0.69 | MAPT (0.51) | ALDH1A1KMT2AKDM4ERAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463100-A | Spraying a mixture of an aminoaryl beta-hydroxyethylsulfone and sulfuric acid into a hot gas stream; drying, esterification and any hydrolysis take place simultaneously; granules | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | claimed |
| EP-0390826-B1 | PROCESS FOR PRODUCING AMINOARYL-BETA-SULPHATOETHYLSULPHONE COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-19 | — | — | EP | claimed |
| US-5463100-A | Spraying a mixture of an aminoaryl beta-hydroxyethylsulfone and sulfuric acid into a hot gas stream; drying, esterification and any hydrolysis take place simultaneously; granules | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |