Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | KIF11 | P52732 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30595083 | 0.87 | LMNA (0.75) | LMNAMAPK1HTTRAB9AAR | |
| SCHEMBL3643490 | 0.87 | LMNA (0.75) | LMNAMAPK1HTTRAB9AAR | |
| SCHEMBL313217 | 0.86 | LMNA (0.73) | LMNAMAPK1HTTRAB9AMAPT | |
| SCHEMBL30837193 | 0.83 | KIF11 (0.54) | LMNAMAPK1HTTRAB9AKIF11 | |
| SCHEMBL31574541 | 0.83 | KIF11 (0.61) | LMNAMAPK1HTTRAB9AKIF11 | |
| SCHEMBL14611048 | 0.82 | AR (0.52) | LMNAMAPK1HTTRAB9AAR | |
| SCHEMBL9464193 | 0.82 | CYP17A1 (0.61) | LMNAMAPK1HTTRAB9AERN1 | |
| SCHEMBL14499485 | 0.81 | FFAR1 (0.49) | LMNAKIF11FFAR1HSD17B1MAPT | |
| SCHEMBL8913485 | 0.80 | KIF11 (0.67) | LMNARAB9AKIF11ERN1HSD17B1 | |
| SCHEMBL20312074 | 0.80 | ERN1 (0.48) | LMNAMAPK1HTTRAB9AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |
| US-5397504-A | Liquid crystal | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0341686-B1 | Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements | JAPAN ENERGY CORP (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5312564-A | Halogen-containing, optically active liquid crystal compound and liquid crystal composition containing same | CHISSO CORPORATION (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0315701-B1 | BIPHENYL COMPOUND | KANTO KAGAKU (JP) | 1993-12-29 | — | — | EP | disclosed |
| EP-0272115-B1 | OPTICALLY ACTIVE LIQUID CRYSTALLINE BIPHENYL COMPOUND | Chisso Corporation (JP) | 1993-10-13 | — | — | EP | disclosed |
| EP-0188222-B1 | NOVEL LIQUID CRISTALLINE COMPOUNDS HAVING SUBSTITUENTS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-04-29 | — | — | EP | disclosed |
| US-5098602-A | Aromatic ester derivatives and fluorophenol ketones | NIPPON MINING CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0231853-B1 | OPTICALLY ACTIVE CARBOXYLIC ACID DERIVATIVES AND LIQUID CRYSTALLINE COMPOSITIONS COMPRISING THEM | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1990-11-22 | — | — | EP | disclosed |
| US-4943386-A | FERROELECTRIC, GOOD RESPONSE AND MEMORY | DAINIPPON INK & CHEMICALS, INC. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4914224-A | HIGH-SPEED RESPONSE, WIDE TEMPERATURE RANGE, CHIRAL SMECTIC PHASES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4911862-A | Aromatic carboxylic ester | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1990-03-27 | — | — | US | disclosed |
| EP-0341686-A2 | Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements | JAPAN ENERGY CORPORATION (JP) | 1989-11-15 | — | — | EP | disclosed |
| EP-0315701-A1 | BIPHENYL COMPOUND | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1989-05-17 | — | — | EP | disclosed |
| US-4828754-A | TILT-TYPE CHIRAL SMECTIC PHASE | DAINIPPON INK & CHEMICALS, INC. (JP) | 1989-05-09 | — | — | US | disclosed |
| US-4780242-A | BIPHENYL ESTERS | CHISSO CORPORATION (JP) | 1988-10-25 | — | — | US | disclosed |
| US-4737313-A | OPITICALLY ACTIVE | CHISSO CORPORATION (JP) | 1988-04-12 | — | — | US | disclosed |
| EP-0231853-A2 | Optically active carboxylic acid derivatives and liquid crystalline compositions comprising them | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1987-08-12 | — | — | EP | disclosed |
| EP-0197677-A2 | Halogen-containing, optically active liquid crystal compound and liquid crystal composition containing same | Chisso Corporation (JP) | 1986-10-15 | — | — | EP | disclosed |
| EP-0188222-A2 | Novel liquid cristalline compounds having substituents | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1986-07-23 | — | — | EP | disclosed |