Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.67 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150363 | 0.85 | KDM4E (0.71) | KIF11HSD17B1MAPTSMN1; SMN2LMNA | |
| SCHEMBL18386420 | 0.84 | KIF11 (0.62) | KIF11HSD17B1MAPTSMN1; SMN2MAOB | |
| SCHEMBL29669896 | 0.83 | CES2 (0.67) | KIF11MAPTMAOBMAOACES2 | |
| SCHEMBL75801 | 0.83 | CES2 (0.67) | KIF11MAPTMAOBMAOACES2 | |
| SCHEMBL2558829 | 0.82 | KIF11 (0.55) | KIF11HSD17B1MAPTSMN1; SMN2LMNA | |
| SCHEMBL2554199 | 0.82 | KIF11 (0.59) | KIF11HSD17B1MAPTSMN1; SMN2LMNA | |
| SCHEMBL15962141 | 0.82 | KIF11 (0.55) | KIF11HSD17B1MAPTSMN1; SMN2MAOB | |
| SCHEMBL2247505 | 0.82 | KDM4E (0.72) | CES2CES1LMNAKDM4EHSD17B10 | |
| SCHEMBL17369440 | 0.82 | CES2 (0.54) | KIF11HSD17B1CES2CES1LMNA | |
| SCHEMBL9149352 | 0.80 | LMNA (0.60) | KIF11HSD17B1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5651919-A | Benzyl ether derivative and composition containing the same | CITIZEN WATCH CO., LTD. (JP) | 1997-07-29 | — | — | US | disclosed |
| US-4125612-A | N-1-(p-Biphenylalkyl)piperazines and their use as anti-inflammatory agents | SCHERING CORPORATION (US) | 1978-11-14 | — | — | US | disclosed |