Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 7/20 | 0.67 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29962586 | 0.90 | ALDH1A1 (0.66) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL500386 | 0.90 | ALDH1A1 (0.66) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL25669903 | 0.89 | ALDH1A1 (0.64) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL29463823 | 0.88 | TOP2A (0.71) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL500719 | 0.88 | TOP2A (0.71) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| Fluoride SCHEMBL5143354 | 0.88 | ALDH1A1 (0.63) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10625970 | 0.88 | TOP2A (0.61) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10511115 | 0.87 | TOP2A (0.69) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| Potassium SCHEMBL10510827 | 0.87 | TOP2A (0.69) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL10511131 | 0.87 | TOP2A (0.69) | TOP2ATOP2BALDH1A1POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551124-B | Quinolone compound or agriculturally and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 山东省联合农药工业有限公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-110551124-A | quinolone compound or agriculturally and pharmaceutically acceptable salt thereof, and preparation method and application thereof | SHANDONG UNITED PESTICIDE IND CO LTD | 2019-12-10 | — | — | CN | disclosed |
| US-5478841-A | Fluorinated quinolones, process for their preparation and pharmaceutical preparations containing same | BOUCHARA S.A. (FR) | 1995-12-26 | — | — | US | disclosed |
| US-5476671-A | Skin disorders | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1995-12-19 | — | — | US | disclosed |