Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.66 |
| ▸ | TOP2A | P11388 | 7/20 | 0.64 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29962586 | 1.00 | ALDH1A1 (0.66) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Fluoride SCHEMBL5143354 | 0.98 | ALDH1A1 (0.63) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL5143359 | 0.96 | ALDH1A1 (0.62) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9149649 | 0.90 | TOP2A (0.67) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL6217009 | 0.90 | ALDH1A1 (0.60) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8091176 | 0.89 | ALDH1A1 (0.54) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL29463823 | 0.88 | TOP2A (0.71) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL500719 | 0.88 | TOP2A (0.71) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL6171288 | 0.88 | TOP2A (0.58) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10330766 | 0.88 | ALDH1A1 (0.63) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989314-B | Method for hydrolyzing quinolone formate | 拜耳动物保健有限责任公司 | 2024-04-30 | — | — | CN | claimed |
| EP-3784656-B1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-06-28 | — | — | EP | claimed |
| US-11332444-B2 | Method for the hydrolysis of quinolonecarboxylic esters | BAYER ANIMAL HEALTH GMBH (DE) | 2022-05-17 | — | — | US | claimed |
| US-20210078950-A1 | METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2021-03-18 | — | — | US | claimed |
| EP-3784656-A1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | Bayer Animal Health GmbH (DE) | 2021-03-03 | — | — | EP | claimed |
| CN-110981853-B | Preparation method of besifloxacin hydrochloride | 安徽赛诺制药有限公司 | 2020-12-22 | — | — | CN | claimed |
| CN-111989314-A | Process for hydrolysis of quinolone formates | 拜耳动物保健有限责任公司 | 2020-11-24 | — | — | CN | claimed |
| CN-110981853-A | Preparation method of besifloxacin hydrochloride | 安徽赛诺制药有限公司 | 2020-04-10 | — | — | CN | claimed |
| US-10167271-B2 | Fluoroquinolone carboxylic acid compounds and use thereof for the preparation of besifloxacin hydrochloride | MANKIND PHARMA LTD (IN) | 2019-01-01 | — | — | US | claimed |
| US-20170362197-A1 | FLUOROQUINOLONE CARBOXYLIC ACID COMPOUNDS AND USE THEREOF FOR THE PREPARATION OF BESIFLOXACIN HYDROCHLORIDE | MANKIND PHARMA LTD (IN) | 2017-12-21 | — | — | US | claimed |
| WO-2016120813-A1 | FLUOROQUINOLONE CARBOXYLIC ACID COMPOUNDS AND USE THEREOF FOR THE PREPARATION OF BESIFLOXACIN HYDROCHLORIDE | MANKIND RESEARCH CENTRE (IN) | 2016-08-04 | — | — | WO | claimed |
| EP-1236718-B1 | Improved process for the preparation of fluoro-quinolonecarboxylic acids | BAYER CHEMICALS AG (DE) | 2004-08-11 | — | — | EP | claimed |
| US-6590101-B2 | Hydrolysis of the corresponding C1-C4-alkyl esters with addition of water, acetic acid, and sulfuric acid using a drastically reduced amount of sulfuric acid | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-08 | — | — | US | claimed |
| EP-1236718-A1 | Improved process for the preparation of fluoro-quinolonecarboxylic acids | BAYER AG (DE) | 2002-09-04 | — | — | EP | claimed |
| US-20020120138-A1 | Process for the preparation of fluoroquinolonecarboxylic acids | LANXESS DEUTSCHLAND GMBH (DE) | 2002-08-29 | — | — | US | claimed |
| US-5468861-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-21 | — | — | US | claimed |
| EP-0167763-B1 | 7-AMINO-1-CYCLOPROPYL-6,8-DIHALO-1,4-DIHYDRO-4-OXO-3-QUINOLINE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND BACTERICIDAL AGENTS CONTAINING THEM | BAYER AG (DE) | 1988-08-03 | — | — | EP | claimed |
| CN-111989314-B | Method for hydrolyzing quinolone formate | 拜耳动物保健有限责任公司 | 2024-04-30 | — | — | CN | disclosed |
| EP-0167763-A1 | 7-Amino-1-cyclopropyl-6,8-dihalo-1,4-dihydro-4-oxo-3-quinoline-carboxylic acids, process for their preparation and bactericidal agents containing them | BAYER AG (DE) | 1986-01-15 | — | — | EP | disclosed |
| EP-0164619-A1 | 2,4,5-Trihalo or 2,3,4,5-tetrahalo benzene derivatives and process for producing them | BAYER AG (DE) | 1985-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120138-A1 | Process for the preparation of fluoroquinolonecarboxylic acids | ADH1C, CTRC, ADH1A | ALDH1A1 124/4885POLB 586/4885OPRM1 1860/4885 |
| US-20210078950-A1 | METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS | NQO2, PGD, ALAD | ALDH1A1 274/4885POLB 172/4885OPRM1 2751/4885 |
| US-10167271-B2 | Fluoroquinolone carboxylic acid compounds and use thereof for the preparation of besifloxacin hydrochloride | NQO2, CYP2F1, Q6ZSR9 | ALDH1A1 1319/4885POLB 1113/4885OPRM1 3296/4885 |
| US-11332444-B2 | Method for the hydrolysis of quinolonecarboxylic esters | NQO2, PGD, ALAD | ALDH1A1 274/4885POLB 172/4885OPRM1 2751/4885 |
| US-20170362197-A1 | FLUOROQUINOLONE CARBOXYLIC ACID COMPOUNDS AND USE THEREOF FOR THE PREPARATION OF BESIFLOXACIN HYDROCHLORIDE | NQO2, CYP2F1, Q6ZSR9 | ALDH1A1 1319/4885POLB 1113/4885OPRM1 3296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.