Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | FFAR2 | O15552 | 10/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350452 | 0.81 | POLB (0.72) | POLBGAARAB9AFFAR2ACE | |
| SCHEMBL23910562 | 0.81 | POLB (0.72) | POLBGAARAB9AFFAR2ACE | |
| SCHEMBL5859631 | 0.81 | POLB (0.72) | POLBGAARAB9AFFAR2ACE | |
| SCHEMBL11100890 | 0.81 | ACE (0.77) | POLBFFAR2ACELMNAALDH1A1 | |
| SCHEMBL11191933 | 0.80 | ACE (0.58) | POLBFFAR2ACELMNAALDH1A1 | |
| SCHEMBL11191943 | 0.73 | ALDH1A1 (0.43) | POLBFFAR2ACELMNAALDH1A1 | |
| SCHEMBL9153332 | 0.72 | POLB (0.45) | POLBGAARAB9AFFAR2ACE | |
| SCHEMBL9853999 | 0.71 | POLB (0.58) | POLBGAARAB9AFFAR2ALDH1A1 | |
| SCHEMBL7186265 | 0.70 | POLB (0.57) | POLBGAARAB9AFFAR2ACE | |
| Acetic Acid SCHEMBL9854087 | 0.70 | POLB (0.57) | POLBGAARAB9AFFAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385922-A | Cardiovascular and gastrointestinal disorders; antiischemic and cardiotonic agents | CEDONA PHARMACEUTICALS B.V. (NL) | 1995-01-31 | — | — | US | disclosed |
| EP-0547104-A1 | THIAZOLIDIN DERIVATIVES | CEDONA PHARMACEUTICALS B.V. (NL) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004337-A1 | THIAZOLIDIN DERIVATIVES | CEDONA PHARMACEUTICALS BV (NL) | 1992-03-19 | — | — | WO | disclosed |