SCHEMBL5859631

SCHEMBL5859631

CC(=O)N1C(C(=O)O)CSC1c1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 3/20 0.72
▸ GAA P10253 2/20 0.72
▸ RAB9A P51151 1/20 0.72
▸ HSD17B10 Q99714 1/20 0.61
▸ FFAR2 O15552 6/20 0.56
▸ ALDH1A1 P00352 3/20 0.48
▸ MEN1 O00255 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ HPGD P15428 1/20 0.47
▸ ACE P12821 2/20 0.46
▸ LMNA P02545 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23910562 1.00 POLB (0.72) POLBGAARAB9AHSD17B10FFAR2
SCHEMBL4350452 1.00 POLB (0.72) POLBGAARAB9AHSD17B10FFAR2
SCHEMBL9853999 0.85 POLB (0.58) POLBGAARAB9AHSD17B10FFAR2
Acetic Acid SCHEMBL9854087 0.84 POLB (0.57) POLBGAARAB9AHSD17B10FFAR2
SCHEMBL11718542 0.84 POLB (0.60) POLBGAARAB9AHSD17B10FFAR2
SCHEMBL11718548 0.84 POLB (0.60) POLBGAARAB9AHSD17B10FFAR2
SCHEMBL11385050 0.83 ACE (0.61) POLBGAARAB9AHSD17B10FFAR2
SCHEMBL9149937 0.81 POLB (0.54) POLBGAARAB9AHSD17B10FFAR2
SCHEMBL8870565 0.81 HSD17B10 (0.57) POLBGAARAB9AHSD17B10FFAR2
SCHEMBL8871013 0.81 HSD17B10 (0.57) POLBGAARAB9AHSD17B10FFAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3727314-B1 DEODORANT COMPOSITIONS UNILEVER IP HOLDINGS B V (NL) 2021-10-13 — — EP claimed
US-20200383891-A1 DEODORANT COMPOSITIONS CONOPCO, INC., D/B/A UNILEVER (US) 2020-12-10 — — US claimed
EP-3727314-A1 DEODORANT COMPOSITIONS Unilever PLC (GB) 2020-10-28 — — EP claimed
US-12246081-B2 Deodorant compositions CONOPCO, INC. (US) 2025-03-11 — — US disclosed
EP-3727314-B1 DEODORANT COMPOSITIONS UNILEVER IP HOLDINGS B V (NL) 2021-10-13 — — EP disclosed
US-20200383891-A1 DEODORANT COMPOSITIONS CONOPCO, INC., D/B/A UNILEVER (US) 2020-12-10 — — US disclosed
EP-3727314-A1 DEODORANT COMPOSITIONS Unilever PLC (GB) 2020-10-28 — — EP disclosed
US-6989384-B2 Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis AGOURON PHARMACEUTICALS, INC. (US) 2006-01-24 — — US disclosed
US-20050080121-A1 Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis AGOURON PHARMACEUTICALS, INC. 2005-04-14 — — US disclosed
EP-1355878-A2 ANTIPICORNAVIRAL COMPOUNDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND MATERIALS FOR THEIR SYNTHESIS AGOURON PHARMACEUTICALS, INC. (US) 2003-10-29 — — EP disclosed
US-6632825-B2 Picornaviral 3C protease enzyme inhibitors; amide ester or amide acid derivatives AGOURON PHARMACEUTICALS, INC. 2003-10-14 — — US disclosed
US-20020061916-A1 Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis AGOURON PHARMACEUTICALS, INC. 2002-05-23 — — US disclosed
WO-2001096297-A2 ANTIPICORNAVIRAL COMPOUNDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND MATERIALS FOR THEIR SYNTHESIS AGOURON PHARMACEUTICALS, INC. (US) 2001-12-20 — — WO disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 — — EP disclosed
US-6197794-B1 ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES CELLTECH THERAPEUTICS LIMITED (GB) 2001-03-06 — — US disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 — — WO disclosed
US-5385922-A Cardiovascular and gastrointestinal disorders; antiischemic and cardiotonic agents CEDONA PHARMACEUTICALS B.V. (NL) 1995-01-31 — — US disclosed
EP-0547104-A1 THIAZOLIDIN DERIVATIVES CEDONA PHARMACEUTICALS B.V. (NL) 1993-06-23 — — EP disclosed
WO-1992004337-A1 THIAZOLIDIN DERIVATIVES CEDONA PHARMACEUTICALS BV (NL) 1992-03-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080121-A1 Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis PRCP, RNPEP, SARNP POLB 505/4885GAA 554/4885RAB9A 2493/4885
US-12246081-B2 Deodorant compositions DHODH, STS, DDT POLB 1758/4885GAA 129/4885RAB9A 2248/4885
US-20020061916-A1 Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis PRCP, RNASEL, RNASEH1 POLB 445/4885GAA 477/4885RAB9A 2679/4885
US-20200383891-A1 DEODORANT COMPOSITIONS DHODH, STS, DDT POLB 1758/4885GAA 129/4885RAB9A 2248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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