Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 11/20 | 0.55 |
| ▸ | MMP13 | P45452 | 3/20 | 0.55 |
| ▸ | MMP3 | P08254 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 12/20 | 0.55 |
| ▸ | MMP8 | P22894 | 2/20 | 0.55 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157760 | 1.00 | TDP1 (0.60) | TDP1MMP2MMP13MMP3MMP9 | |
| SCHEMBL255603 | 0.85 | MMP9 (0.74) | TDP1MMP2MMP13MMP3MMP9 | |
| SCHEMBL951767 | 0.85 | TDP1 (0.60) | TDP1MMP2MMP13MMP3MMP9 | |
| SCHEMBL951766 | 0.85 | TDP1 (0.60) | TDP1MMP2MMP13MMP3MMP9 | |
| SCHEMBL5182861 | 0.85 | MMP9 (0.74) | TDP1MMP2MMP13MMP3MMP9 | |
| SCHEMBL697840 | 0.85 | MMP9 (0.74) | TDP1MMP2MMP13MMP3MMP9 | |
| SCHEMBL25961785 | 0.85 | CA2 (0.50) | TDP1MMP2MMP13MMP3MMP9 | |
| SCHEMBL9272964 | 0.85 | CA2 (0.50) | TDP1MMP2MMP13MMP3MMP9 | |
| SCHEMBL6940563 | 0.84 | PLAU (0.61) | TDP1MMP2MMP13MMP3MMP9 | |
| Water SCHEMBL30893957 | 0.84 | MMP9 (0.72) | TDP1MMP2MMP13MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442088-A | Reacting optically active S-homoserine lactone with hydrogen chloride in the presence of an alcohol, and reacting the resulting halogen substituted compound with a phosphorus compound | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-15 | — | — | US | disclosed |