SCHEMBL255603

SCHEMBL255603

Cc1ccc(S(=O)(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1

nearest known ligand 0.74

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 13/20 0.74
MMP8 P22894 4/20 0.74
MMP13 P45452 2/20 0.74
ADAMTS4 O75173 1/20 0.74
MMP2 P08253 13/20 0.60
TDP1 Q9NUW8 2/20 0.60
SMN1; SMN2 Q16637 1/20 0.58
MMP12 P39900 3/20 0.55
MMP14 P50281 3/20 0.55
MMP3 P08254 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.54
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
SLC1A1 P43005 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL697840 1.00 MMP9 (0.74) MMP9MMP8MMP13ADAMTS4MMP2
SCHEMBL5182861 1.00 MMP9 (0.74) MMP9MMP8MMP13ADAMTS4MMP2
Water SCHEMBL30893957 0.99 MMP9 (0.72) MMP9MMP8MMP13ADAMTS4MMP2
SCHEMBL28937664 0.99 MMP9 (0.72) MMP9MMP8MMP13ADAMTS4MMP2
SCHEMBL29186820 0.99 MMP9 (0.72) MMP9MMP8MMP13ADAMTS4MMP2
Toluene SCHEMBL7906483 0.96 MMP9 (0.78) MMP9MMP8MMP13ADAMTS4MMP2
SCHEMBL8448575 0.92 MMP2 (0.67) MMP9MMP8MMP13ADAMTS4MMP2
SCHEMBL3458998 0.89 MMP9 (0.76) MMP9MMP8MMP13ADAMTS4MMP2
SCHEMBL21538609 0.89 MMP9 (0.76) MMP9MMP8MMP13ADAMTS4MMP2
Potassium Ion SCHEMBL30893958 0.89 MMP9 (0.59) MMP9MMP8MMP13ADAMTS4MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346566-A1 Process For Preparation of Imeglimin and Salts Thereof HARMAN FINOCHEM LTD (IN) 2025-11-13 US claimed
EP-4514392-A1 PROCESS FOR PREPARATION OF IMEGLIMIN AND SALTS THEREOF Harman Finochem Limited (IN) 2025-03-05 EP claimed
CN-117800881-A Recovery method of levamisole hydrochloride resolving agent N-p-toluenesulfonyl-L- (+) -glutamic acid 常州齐晖药业有限公司 2024-04-02 CN claimed
WO-2023209729-A1 PROCESS FOR PREPARATION OF IMEGLIMIN AND SALTS THEREOF HARMAN FINOCHEM LIMITED (IN) 2023-11-02 WO claimed
US-20190002394-A1 SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF CODY LABORATORIES, INC. 2019-01-03 US claimed
US-10040752-B2 Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof CODY LABORATORIES, INC. (US) 2018-08-07 US claimed
EP-3341354-A1 SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF Cody Laboratories, Inc. (US) 2018-07-04 EP claimed
WO-2017035224-A1 SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF CODY LABORATORIES, INC. (US) 2017-03-02 WO claimed
US-20170057909-A1 SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF ALTER DOMUS (US) LLC 2017-03-02 US claimed
CN-100341850-C Salts of demethyl phencynonate isomer and N-para-methyl-phenyl-sulfuryl glutamic acid optical isomer and their preparing method and use INST OF POISONOUS MEDICINE ACA (CN) 2007-10-10 CN claimed
CN-1781904-A Salts of demethyl phencynonate isomer and N-para-methyl-phenyl-sulfuryl glutamic acid optical isomer and their preparing method and use INST OF POISONOUS MEDICINE ACA (CN) 2006-06-07 CN claimed
EP-1457487-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE CIS-PIPERIDINE DERIVATIVES Toray Fine Chemicals Co., Ltd. (JP) 2004-09-15 EP claimed
US-20040171836-A1 Method for producing optical-active cis-piperidine derivatives TORAY FINE CHEMICALS CO., LTD., A CORPORATION OF JAPAN, (JP) 2004-09-02 US claimed
US-20250346566-A1 Process For Preparation of Imeglimin and Salts Thereof HARMAN FINOCHEM LTD (IN) 2025-11-13 US disclosed
EP-4514392-A1 PROCESS FOR PREPARATION OF IMEGLIMIN AND SALTS THEREOF Harman Finochem Limited (IN) 2025-03-05 EP disclosed
CN-119285523-A Method for recovering tetramisole hydrochloride resolving agent N-p-toluenesulfonyl-L-proline 河北尚澳生物科技有限公司 2025-01-10 CN disclosed
US-4206118-A Method for racemissing d (or l) tetramisole, and the relative product MARXER S.P.A. (IT) 1980-06-03 US disclosed
EP-0009702-A1 A phenylalkylaminoethylsalicylamide, its preparation and pharmaceutical compositions containing it SCHERING CORPORATION (US) 1980-04-16 EP disclosed
US-4179569-A ANALGESIC INTERMEDIATES JANSSEN PHARMACEUTICA N.V. (BE) 1979-12-18 US disclosed
US-3998834-A ANALGESICS JANSSEN PHARMACEUTICA N.V. (BE) 1976-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170057909-A1 SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF CYP2D6, COMT, AADAT MMP9 4493/4885MMP8 3083/4885MMP13 3702/4885
US-20040171836-A1 Method for producing optical-active cis-piperidine derivatives TYR, DDC, TARBP1 MMP9 1373/4885MMP8 2925/4885MMP13 1152/4885
US-20250346566-A1 Process For Preparation of Imeglimin and Salts Thereof GCG, VIP, IAPP MMP9 1191/4885MMP8 3627/4885MMP13 1696/4885
US-20190002394-A1 SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF CYP2D6, COMT, AADAT MMP9 4493/4885MMP8 3083/4885MMP13 3702/4885
US-10040752-B2 Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof CYP2D6, COMT, AADAT MMP9 4493/4885MMP8 3083/4885MMP13 3702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.