Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30364439 | 0.78 | HTT (0.43) | CYP2C9CYP3A4CYP2C19HSP90AA1MEN1 | |
| SCHEMBL27381778 | 0.73 | KMT2A (0.46) | CYP2C9CYP3A4CYP2C19HSP90AA1MEN1 | |
| SCHEMBL8911620 | 0.72 | CYP2C9 (0.41) | CYP2C9CYP3A4CYP2C19HSP90AA1MEN1 | |
| SCHEMBL15069913 | 0.72 | CRHR1 (0.43) | CYP2C9CYP3A4CYP2C19HSP90AA1MEN1 | |
| SCHEMBL30917263 | 0.72 | CRHR1 (0.43) | CYP2C9CYP3A4CYP2C19HSP90AA1MEN1 | |
| SCHEMBL9716976 | 0.68 | CHRNA7 (0.40) | CYP2C9CYP3A4CYP2C19HSP90AA1MEN1 | |
| SCHEMBL27699836 | 0.64 | CHRNA7 (0.41) | CYP2C9CYP3A4CYP2C19HSP90AA1MEN1 | |
| SCHEMBL3102522 | 0.64 | HSP90AA1 (0.83) | CYP2C9CYP3A4CYP2C19HSP90AA1MEN1 | |
| SCHEMBL9118942 | 0.64 | CYP2C9 (0.48) | CYP2C9CYP3A4CYP2C19HSP90AA1MEN1 | |
| SCHEMBL29748943 | 0.64 | HSP90AA1 (0.83) | CYP2C9CYP3A4CYP2C19HSP90AA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7145152-A | — | — | None | — | — | JP | disclosed |
| JP-H07145152-A | 3,4-DIHYDRO-1-(2-HYDROXYPHENYL)-2(1H)-QUINOXALINONE DERIVATIVE AND ITS RELATED COMPOUND | DAINIPPON PHARMACEUT CO LTD | 1995-06-06 | — | — | JP | disclosed |