Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15069913 | 1.00 | CRHR1 (0.43) | CRHR1TMPRSS4CHRNA7KMT2AMEN1 | |
| SCHEMBL8911620 | 0.75 | CYP2C9 (0.41) | TMPRSS4CHRNA7KMT2AMEN1MAPT | |
| SCHEMBL9150322 | 0.72 | CYP2C9 (0.39) | TMPRSS4CHRNA7KMT2AMEN1MAPT | |
| SCHEMBL30364439 | 0.71 | HTT (0.43) | TMPRSS4CHRNA7KMT2AMEN1MAPT | |
| SCHEMBL8998844 | 0.69 | LMNA (0.54) | KMT2AMEN1AADATNOTUM | |
| SCHEMBL248856 | 0.68 | NOTUM (0.56) | CRHR1MAPTAADATTSHRNOTUM | |
| SCHEMBL7893735 | 0.68 | AADAT (0.47) | CRHR1KMT2AMEN1MAPTP2RX4 | |
| SCHEMBL5857447 | 0.68 | OPRK1 (0.41) | KMT2AMEN1MAPTALOX12HSP90AA1 | |
| SCHEMBL27699836 | 0.67 | CHRNA7 (0.41) | TMPRSS4CHRNA7KMT2AMEN1MAPT | |
| SCHEMBL3102522 | 0.67 | HSP90AA1 (0.83) | TMPRSS4KMT2AMEN1MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11988661-B2 | Rapid quantitative test to diagnose polycystic kidney disease | UMC UTRECHT HOLDING, B.V. (NL) | 2024-05-21 | — | — | US | disclosed |