Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TMPRSS4 | Q9NRS4 | 7/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 7/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15069913 | 0.75 | CRHR1 (0.43) | CYP2C9HSP90AA1MEN1KMT2ACYP1A2 | |
| SCHEMBL30917263 | 0.75 | CRHR1 (0.43) | CYP2C9HSP90AA1MEN1KMT2ACYP1A2 | |
| SCHEMBL9150322 | 0.72 | CYP2C9 (0.39) | CYP2C9HSP90AA1MEN1KMT2ACYP1A2 | |
| SCHEMBL30364439 | 0.71 | HTT (0.43) | CYP2C9HSP90AA1MEN1KMT2ACYP1A2 | |
| SCHEMBL5754955 | 0.70 | COMT (0.44) | CYP2C9HSP90AA1MEN1KMT2ACYP1A2 | |
| SCHEMBL7954476 | 0.70 | HSP90AA1 (0.44) | CYP2C9HSP90AA1MEN1KMT2ACYP1A2 | |
| SCHEMBL5541636 | 0.69 | HCAR1 (0.39) | CYP2C9HSP90AA1MEN1KMT2ACYP1A2 | |
| SCHEMBL27699836 | 0.69 | CHRNA7 (0.41) | CYP2C9HSP90AA1MEN1KMT2ACYP1A2 | |
| SCHEMBL29748943 | 0.69 | HSP90AA1 (0.83) | CYP2C9HSP90AA1MEN1KMT2ACYP1A2 | |
| SCHEMBL29948904 | 0.69 | HSP90AA1 (0.83) | CYP2C9HSP90AA1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621007-A | Method for regulation of transmembrane chloride conductance | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-04-15 | — | — | US | disclosed |