Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8214372 | 0.80 | CA12 (0.50) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL9699314 | 0.79 | TSHR (0.42) | SLC6A4SLC6A2MEN1KMT2AGAA | |
| SCHEMBL668348 | 0.79 | TRPV4 (0.48) | TRPV4SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL9151398 | 0.74 | SMN1; SMN2 (0.38) | LMNAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29433653 | 0.73 | CA1 (0.48) | LMNAALDH1A1HTTTDP1 | |
| SCHEMBL2332056 | 0.73 | CA1 (0.48) | LMNAALDH1A1HTTTDP1 | |
| SCHEMBL8722412 | 0.72 | CA12 (0.54) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL8164294 | 0.72 | CA1 (0.46) | LMNAALDH1A1HTTTDP1 | |
| SCHEMBL8335436 | 0.71 | CA12 (0.48) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL2827783 | 0.71 | CA1 (0.41) | LMNAALDH1A1MAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434117-A | Catalyst system and copolymerization process | SHELL OIL COMPANY (US) | 1995-07-18 | — | — | US | disclosed |