Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150373 | 0.74 | TRPV4 (0.42) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL2325597 | 0.73 | ACHE (0.52) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL30680643 | 0.73 | ACHE (0.52) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL29587813 | 0.72 | GLA (0.53) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL8233721 | 0.72 | GLA (0.53) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL92053 | 0.71 | KMT2A (0.47) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL13696483 | 0.69 | PDE4A (0.47) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL7178003 | 0.68 | ALDH1A1 (0.51) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL8214372 | 0.68 | CA12 (0.50) | MAPTKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL22593272 | 0.67 | TAAR1 (0.48) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434117-A | Catalyst system and copolymerization process | SHELL OIL COMPANY (US) | 1995-07-18 | — | — | US | disclosed |