Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150373 | 0.79 | TRPV4 (0.42) | HPGDMAPTSLC6A2SLC6A4GAA | |
| SCHEMBL10386825 | 0.78 | KDM4E (0.45) | TSHRHPGDMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10540535 | 0.75 | ALDH1A1 (0.47) | HPGDMAPTCYP1A2CYP2D6GAA | |
| SCHEMBL2525158 | 0.74 | TSHR (0.56) | TSHRHPGDMAPTHTR2CHTR2B | |
| SCHEMBL9700354 | 0.74 | KDM4E (0.47) | TSHRHPGDMAPTCYP1A2MEN1 | |
| SCHEMBL1311327 | 0.72 | TSHR (0.50) | TSHRHPGDMAPTHTR2CHTR2B | |
| SCHEMBL29483410 | 0.72 | TSHR (0.50) | TSHRHPGDMAPTHTR2CHTR2B | |
| SCHEMBL30680642 | 0.72 | ALDH1A1 (0.47) | HPGDMAPTCYP1A2CYP2D6GAA | |
| SCHEMBL8371903 | 0.72 | ALDH1A1 (0.47) | HPGDMAPTCYP1A2CYP2D6GAA | |
| SCHEMBL10304975 | 0.71 | TSHR (0.49) | TSHRHPGDMAPTHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116797-A | POLYMERIZATION PROCESS | SHELL OIL COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| US-5010170-A | Polymerization of carbon monoxide/olefin with at least one tetra aryl diphosphine ligand | SHELL OIL COMPANY (US) | 1991-04-23 | — | — | US | disclosed |