Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19055422 | 0.79 | HSD17B10 (0.38) | HSD17B10NISCHKMT2A | |
| SCHEMBL18209131 | 0.79 | PNMT (0.40) | HSD17B10KMT2A | |
| SCHEMBL17055870 | 0.79 | PNMT (0.40) | HSD17B10KMT2A | |
| SCHEMBL17055852 | 0.79 | HSD17B10 (0.38) | HSD17B10NISCHKMT2A | |
| SCHEMBL6969139 | 0.78 | HTR1A (0.48) | MTNR1AHRH3HTR1ACDK1MAPKAPK2 | |
| SCHEMBL7476692 | 0.75 | CASR (0.45) | HTR1ANISCHGAA | |
| SCHEMBL20687582 | 0.74 | ALDH1A1 (0.40) | MTNR1AHRH3HTR1AHSD17B10NISCH | |
| SCHEMBL11545591 | 0.74 | HPGD (0.48) | HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL13757108 | 0.73 | HSD17B10 (0.38) | HTR1AHSD17B10GAAMAPTMEN1 | |
| SCHEMBL13757112 | 0.73 | HSD17B10 (0.38) | HTR1AHSD17B10GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5474988-A | Analgesics, antiinflammatory agents | KALI-CHEMIE PHARMA GMBH (DE) | 1995-12-12 | — | — | US | disclosed |
| EP-0614899-A1 | 5-Phenyl-pyrrolo-1,4-benzoxazine and thiazine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | Kali-Chemie Pharma GmbH (DE) | 1994-09-14 | — | — | EP | disclosed |