Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150705 | 0.78 | HDAC4 (0.37) | TSHR | |
| SCHEMBL107837 | 0.75 | HDAC4 (0.36) | TSHR | |
| SCHEMBL9008779 | 0.73 | THRB (0.42) | THRBCA1CA2TSHRALDH1A1 | |
| SCHEMBL13567318 | 0.72 | THRB (0.40) | THRBCA1CA2TSHRALDH1A1 | |
| SCHEMBL9153880 | 0.71 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL21890930 | 0.70 | THRB (0.40) | THRBCA1CA2TSHRALDH1A1 | |
| SCHEMBL9816089 | 0.70 | TSHR (0.38) | EPHX1TSHRALDH1A1 | |
| SCHEMBL9149131 | 0.70 | GAA (0.39) | TSHR | |
| SCHEMBL5074348 | 0.69 | ALDH1A1 (0.47) | THRBTSHRALDH1A1 | |
| SCHEMBL14885808 | 0.68 | THRB (0.38) | THRBCA1CA2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397821-A | Light and heat stabilizers, low volatility | ELFATOCHEM NORTH AMERICA, INC. (US) | 1995-03-14 | — | — | US | disclosed |
| US-5338853-A | N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-08-16 | — | — | US | disclosed |