Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 8/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13331904 | 0.99 | ALDH1A1 (0.48) | ALDH1A1PTGER4PTGER3PTGER2ADRA1A | |
| SCHEMBL9654682 | 0.90 | ALDH1A1 (0.42) | ALDH1A1PTGER4PTGER3PTGER2ADRA1A | |
| SCHEMBL3767009 | 0.84 | PTGER4 (0.46) | ALDH1A1PTGER4PTGER3PTGER2ADRA1A | |
| SCHEMBL242586 | 0.82 | MEN1 (0.51) | ALDH1A1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL8761610 | 0.82 | MEN1 (0.51) | ALDH1A1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL8754825 | 0.82 | MEN1 (0.51) | ALDH1A1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL8761679 | 0.82 | MEN1 (0.51) | ALDH1A1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL8761736 | 0.82 | MEN1 (0.51) | ALDH1A1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL3425106 | 0.82 | MEN1 (0.51) | ALDH1A1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL8749215 | 0.82 | MEN1 (0.51) | ALDH1A1PTGER4PTGER3PTGER2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472946-A | Topical administration of lincomycin, clindamycin, erthromycin and iododeoxyuridine on skin or mucuous membranes | DISCOVERY THERAPEUTICS, INC. | 1995-12-05 | — | — | US | disclosed |