Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | NT5C2 | P49902 | 2/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triphosphate SCHEMBL19057041 | 0.87 | PI4KA (0.44) | F7F3SARM1SIRT2SIRT6 | |
| Adenine SCHEMBL755727 | 0.85 | PI4KA (0.46) | F7F3SARM1SIRT2SIRT6 | |
| Hypoxanthine SCHEMBL9150757 | 0.82 | SIRT2 (0.50) | F7F3SARM1SIRT2SIRT6 | |
| Adenine SCHEMBL1408059 | 0.80 | PI4KA (0.50) | F7F3SARM1SIRT2SIRT6 | |
| Adenine SCHEMBL27528672 | 0.80 | PI4KA (0.50) | F7F3SARM1SIRT2SIRT6 | |
| Niacinamide SCHEMBL28907028 | 0.78 | SIRT2 (0.47) | F7F3SARM1SIRT2SIRT6 | |
| Adenine SCHEMBL15700 | 0.78 | PI4KA (0.55) | F7F3SARM1SIRT2SIRT6 | |
| Adenine SCHEMBL22748487 | 0.78 | PI4KA (0.55) | F7F3SARM1SIRT2SIRT6 | |
| Adenine SCHEMBL2564210 | 0.78 | PI4KA (0.55) | F7F3SARM1SIRT2SIRT6 | |
| Adenine SCHEMBL23531102 | 0.77 | PI4KA (0.54) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471740-B1 | ENZYMES AND THEIR USE IN DRUG DETECTION | BRITISH TECH GROUP (GB) | 1995-08-09 | — | — | EP | disclosed |
| US-5387515-A | Oxidation in the presence of the enzyme and cofactor nadp | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-02-07 | — | — | US | disclosed |
| US-5298414-A | Polypeptides, oxidation for detection | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-03-29 | — | — | US | disclosed |