Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421904 | 0.79 | MAPT (0.42) | FDFT1MAPTTDP1POLBHTT | |
| Hydrochloric Acid SCHEMBL8772602 | 0.79 | FDFT1 (0.42) | FDFT1MAPTHTTMEN1ALDH1A1 | |
| SCHEMBL8423284 | 0.78 | FDFT1 (0.41) | FDFT1CHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL8421585 | 0.78 | FDFT1 (0.41) | FDFT1MAPTTDP1CHRM2CHRM4 | |
| SCHEMBL8421714 | 0.78 | MAPT (0.42) | FDFT1MAPTTDP1POLBHTT | |
| SCHEMBL9150829 | 0.78 | FDFT1 (0.41) | FDFT1MAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL8772751 | 0.77 | FDFT1 (0.37) | FDFT1MAPTTDP1CHRM2CHRM4 | |
| SCHEMBL8772748 | 0.77 | FDFT1 (0.37) | FDFT1MAPTTDP1CHRM2CHRM4 | |
| SCHEMBL8422017 | 0.77 | FDFT1 (0.39) | FDFT1MAPTTDP1CHRM2CHRM4 | |
| SCHEMBL8772704 | 0.77 | FDFT1 (0.37) | FDFT1CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654032-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS. | ZENECA LTD (GB) | 1995-05-24 | — | — | EP | disclosed |