Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530575 | 0.86 | SMN1; SMN2 (0.58) | SMN1; SMN2CA1CA5ACA2CYP1A2 | |
| SCHEMBL15318479 | 0.83 | CA5A (0.62) | CA1CA5ACA2TPSAB1PLG | |
| SCHEMBL10954836 | 0.83 | CA5A (0.62) | CA1CA5ACA2TPSAB1PLG | |
| SCHEMBL7368539 | 0.81 | CA1 (0.57) | SMN1; SMN2CA1CA5ACA2TPSAB1 | |
| SCHEMBL10954266 | 0.81 | CA5A (0.60) | CA1CA5ACA2TPSAB1PLG | |
| SCHEMBL9136357 | 0.79 | CTSK (0.62) | TPSAB1PLGPRSS1CYP1A2CTSK | |
| SCHEMBL6914499 | 0.79 | CYP1A2 (0.54) | TPSAB1PLGPRSS1CYP1A2ELANE | |
| SCHEMBL7368908 | 0.79 | LMNA (0.46) | SMN1; SMN2CA1CA2 | |
| SCHEMBL9150862 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2CA1CA2MMP3 | |
| SCHEMBL9156183 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2CA1CA2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438047-A | Diphosphates of catecholamines and pharmaceutical compositions containing them | ZAMBON GROUP S.P.A. (IT) | 1995-08-01 | — | — | US | disclosed |
| EP-0607394-A1 | DIPHOSPHATES OF CATECHOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994003461-A1 | DIPHOSPHATES OF CATECHOLAMINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.P.A. (IT) | 1994-02-17 | — | — | WO | disclosed |