Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 6/20 | 0.66 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4611780 | 0.98 | ACHE (0.68) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| Bromide SCHEMBL30267654 | 0.81 | ACHE (0.56) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| SCHEMBL9351826 | 0.80 | ACHE (0.56) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| SCHEMBL4611923 | 0.79 | ACHE (0.71) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| Edrophonium SCHEMBL29627074 | 0.79 | ACHE (1.00) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| Edrophonium SCHEMBL34790 | 0.79 | ACHE (1.00) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| Edrophonium SCHEMBL8009388 | 0.79 | ACHE (1.00) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| Edrophonium SCHEMBL19148596 | 0.78 | ACHE (1.00) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| Edrophonium SCHEMBL34789 | 0.78 | ACHE (1.00) | ACHETSHROPRM1BLMSMN1; SMN2 | |
| Edrophonium SCHEMBL10893553 | 0.78 | ACHE (0.96) | ACHETSHROPRM1BLMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328391-B1 | Stabilizers for photographic emulsions | MINNESOTA MINING & MFG (US) | 1995-01-11 | — | — | EP | disclosed |
| US-4988615-A | Stabilizers for photographic emulsions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0328391-A2 | Stabilizers for photographic emulsions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-08-16 | — | — | EP | disclosed |