Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.44 |
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22860845 | 0.99 | TDP1 (0.69) | TDP1L3MBTL1KIF20BACE2PTPN1 | |
| SCHEMBL29661452 | 0.84 | TDP1 (0.51) | TDP1L3MBTL1KIF20BACE2PTPN1 | |
| SCHEMBL22860858 | 0.84 | TDP1 (0.51) | TDP1L3MBTL1KIF20BACE2PTPN1 | |
| SCHEMBL29661466 | 0.82 | TDP1 (0.55) | TDP1L3MBTL1KIF20BACE2PTPN1 | |
| SCHEMBL22860852 | 0.82 | TDP1 (0.55) | TDP1L3MBTL1KIF20BACE2PTPN1 | |
| SCHEMBL22860829 | 0.82 | TDP1 (0.49) | TDP1L3MBTL1KIF20BACE2PTPN1 | |
| SCHEMBL4923792 | 0.74 | PTGS2 (0.61) | TDP1ALOX5PTGS2GPR84 | |
| SCHEMBL9155082 | 0.74 | ALDH1A1 (0.57) | TDP1L3MBTL1PTPN1 | |
| SCHEMBL9286375 | 0.72 | CYP19A1 (0.53) | TDP1L3MBTL1PTPN1 | |
| SCHEMBL22860835 | 0.69 | L3MBTL1 (0.46) | TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5386019-A | Reacting a sugar glycal with a 2,4-dihydroxybenzoic acid derivative, and combining the aryl glycoside formed with a suitable aryl compound | YALE UNIVERSITY (US) | 1995-01-31 | — | — | US | disclosed |
| WO-1993014099-A1 | SYNTHESIS OF INHIBITORS OF CALMODULIN-MEDIATED ENZYMES | YALE UNIVERSITY (US) | 1993-07-22 | — | — | WO | disclosed |