Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PRCP | P42785 | 3/20 | 0.53 |
| ▸ | HTR2C | P28335 | 5/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750286 | 1.00 | KMT2A (0.55) | KMT2APRCPHTR2CHTR2BTLR2 | |
| SCHEMBL2143309 | 0.95 | KMT2A (0.53) | KMT2APRCPHTR2CHTR2BTLR2 | |
| SCHEMBL14365127 | 0.84 | PRCP (0.54) | PRCPHTR2CHTR2BTLR2TERT | |
| SCHEMBL26372705 | 0.84 | PRCP (0.54) | PRCPHTR2CHTR2BTLR2TERT | |
| SCHEMBL1329146 | 0.83 | PRCP (0.57) | KMT2APRCPHTR2CHTR2BTLR2 | |
| SCHEMBL26372714 | 0.81 | KMT2A (0.39) | KMT2APRCPHTR2CHTR2BNPSR1 | |
| SCHEMBL4728475 | 0.80 | PRCP (0.57) | PRCPHTR2CHTR2BTLR2TERT | |
| SCHEMBL2373740 | 0.80 | PRCP (0.57) | PRCPHTR2CHTR2BTLR2TERT | |
| SCHEMBL15329272 | 0.80 | PRCP (0.70) | PRCPHTR2CHTR2BTLR2TERT | |
| SCHEMBL615383 | 0.78 | PRCP (0.68) | KMT2APRCPHTR2CHTR2BTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468876-A | Intermediates for the stereoconservative synthesis of 1-substituted (S)-and (R)-2-aminomethylpyrrolidines | AKTIEBOLAGET ASTRA (SE) | 1995-11-21 | — | — | US | disclosed |
| US-5300660-A | Efficient stereoconservative synthesis of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines and intermediates thereto | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1994-04-05 | — | — | US | disclosed |
| EP-0253785-B1 | EFFICIENT STEREOCONSERVATIVE SYNTHESES OF 1-SUBSTITUTED (S)- AND (R)-2-AMINOMETHYLPYRROLIDINES AND INTERMEDIATES THEREIN | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0253785-A1 | Efficient stereoconservative syntheses of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines and intermediates therein | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1988-01-20 | — | — | EP | disclosed |