SCHEMBL4728475

SCHEMBL4728475

[CH2]CNC(=O)[C@@H]1CCCN1

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRCP P42785 3/20 0.57
HTR2C P28335 6/20 0.49
HTR2B P41595 3/20 0.49
TLR2 O60603 2/20 0.44
TERT O14746 1/20 0.44
DPP7 Q9UHL4 1/20 0.43
KDM4E B2RXH2 1/20 0.43
HTR2A P28223 1/20 0.40
CTSC P53634 1/20 0.40
NOS2 P35228 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2373740 1.00 PRCP (0.57) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL15329272 0.84 PRCP (0.70) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL615383 0.82 PRCP (0.68) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL943040 0.82 PRCP (0.58) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL496387 0.82 PRCP (0.68) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL616732 0.82 PRCP (0.68) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL12529945 0.81 PRCP (0.57) PRCPHTR2CHTR2BTLR2TERT
Hydrochloric Acid SCHEMBL4320225 0.81 PRCP (0.66) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL9151671 0.80 KMT2A (0.55) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL26372081 0.80 PRCP (0.53) PRCPHTR2CHTR2BTLR2TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11896704-B2 Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-02-13 US disclosed
EP-3648784-B1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES LUBRIZOL ADVANCED MAT INC (US) 2021-12-22 EP disclosed
US-20210244639-A1 A COSMETIC HAIR DYEING AND/OR BLEACHING COMPOSITION, METHOD, USE AND KIT THEREOF MUFG BANK LTD. AS AGENT 2021-08-12 US disclosed
EP-2928484-B1 COMPOUNDS USEFUL IN THE TREATMENT AND/OR CARE OF THE SKIN, HAIR AND/OR MUCOUS MEMBRANES AND THEIR COSMETIC OR PHARMACEUTICAL COMPOSITIONS LUBRIZOL ADVANCED MAT INC (US) 2021-03-24 EP disclosed
EP-3784207-A1 A COSMETIC HAIR DYEING AND/OR BLEACHING COMPOSITION, METHOD, USE AND KIT THEREOF Revlon (US) 2021-03-03 EP disclosed
US-10799442-B2 Compounds useful in the treatment and/or care of the skin, hair, nails, and/or mucous membranes LUBRIZOL ADVANCED MATERIALS, INC. (US) 2020-10-13 US disclosed
US-20200214960-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2020-07-09 US disclosed
EP-3648784-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES Lubrizol Advanced Materials, Inc. (US) 2020-05-13 EP disclosed
US-20200046625-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2020-02-13 US disclosed
EP-3526231-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES Lubrizol Advanced Materials, Inc. (US) 2019-08-21 EP disclosed
WO-2018071640-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2018-04-19 WO disclosed
WO-2017100421-A1 COMPOUNDS USEFUL IN THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS, AND/OR MUCOUS MEMBRANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2017-06-15 WO disclosed
US-9511010-B2 Compounds useful in the treatment and/or care of the skin, hair and/or mucous membranes and their cosmetic or pharmaceutical compositions LUBRIZOL ADVANCED MATERIALS, INC. (US) 2016-12-06 US disclosed
US-20150342852-A1 COMPOUNDS USEFUL IN THE TREATMENT AND/OR CARE OF THE SKIN, HAIR AND/OR MUCOUS MEMBRANES AND THEIR COSMETIC OR PHARMACEUTICAL COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. 2015-12-03 US disclosed
EP-2928484-A1 COMPOUNDS USEFUL IN THE TREATENT AND/OR CARE OF THE SKIN, HAIR AND/OR MUCOUS MEMBRANES AND THEIR COSMETIC OR PHARMACEUTICAL COMPOSITIONS Lubrizol Advanced Materials, Inc. (US) 2015-10-14 EP disclosed
WO-2014086785-A1 COMPOUNDS USEFUL IN THE TREATENT AND/OR CARE OF THE SKIN, HAIR AND/OR MUCOUS MEMBRANES AND THEIR COSMETIC OR PHARMACEUTICAL COMPOSITIONS LIPOTEC S.A. (ES) 2014-06-12 WO disclosed
EP-2740484-A1 Compounds useful in the treatment and/or care of the skin, hair and/or muccous membranes and their cosmetic or pharmaceutical compositions Lipotec, S.A. (ES) 2014-06-11 EP disclosed
US-20080075798-A1 Personal care compositions comprising pear seed extract PROCTER & GAMBLE COMPANY, THE 2008-03-27 US disclosed
WO-2008027533-A2 PERSONAL CARE COMPOSITIONS COMPRISING PEAR SEED EXTRACT THE PROCTER & GAMBLE COMPANY (US) 2008-03-06 WO disclosed
US-6423725-B1 ANALGESICS PFIZER INC 2002-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200046625-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES CUTA, MCOLN3, MC3R PRCP 2183/4885HTR2C 493/4885HTR2B 825/4885
US-11896704-B2 Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes TYR, MTX1, MTX2 PRCP 3528/4885HTR2C 869/4885HTR2B 1500/4885
US-20150342852-A1 COMPOUNDS USEFUL IN THE TREATMENT AND/OR CARE OF THE SKIN, HAIR AND/OR MUCOUS MEMBRANES AND THEIR COSMETIC OR PHARMACEUTICAL COMPOSITIONS TYR, MC1R, ZYX PRCP 2061/4885HTR2C 791/4885HTR2B 1598/4885
US-10799442-B2 Compounds useful in the treatment and/or care of the skin, hair, nails, and/or mucous membranes TYR, ZYX, DPM1 PRCP 3193/4885HTR2C 1098/4885HTR2B 2194/4885
US-20080075798-A1 Personal care compositions comprising pear seed extract CUTA, POLR1C, DPM1 PRCP 2041/4885HTR2C 3181/4885HTR2B 4324/4885
US-20200214960-A1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES TYR, MTX2, MTX1 PRCP 3561/4885HTR2C 748/4885HTR2B 1370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.