SCHEMBL2373740

SCHEMBL2373740

[CH2]CNC(=O)C1CCCN1

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRCP P42785 3/20 0.57
HTR2C P28335 6/20 0.49
HTR2B P41595 3/20 0.49
TLR2 O60603 2/20 0.44
TERT O14746 1/20 0.44
DPP7 Q9UHL4 1/20 0.43
KDM4E B2RXH2 1/20 0.43
HTR2A P28223 1/20 0.40
CTSC P53634 1/20 0.40
NOS2 P35228 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4728475 1.00 PRCP (0.57) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL15329272 0.84 PRCP (0.70) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL615383 0.82 PRCP (0.68) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL943040 0.82 PRCP (0.58) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL496387 0.82 PRCP (0.68) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL616732 0.82 PRCP (0.68) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL12529945 0.81 PRCP (0.57) PRCPHTR2CHTR2BTLR2TERT
Hydrochloric Acid SCHEMBL4320225 0.81 PRCP (0.66) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL9151671 0.80 KMT2A (0.55) PRCPHTR2CHTR2BTLR2TERT
SCHEMBL26372081 0.80 PRCP (0.53) PRCPHTR2CHTR2BTLR2TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2978767-B1 DYEING METHOD USING A HAIR-DYEING PRECURSOR OBTAINED FROM IRIDOIDS, COMPOSITION, PRECURSOR AND DEVICE INCLUDING SAME OREAL (FR) 2018-10-03 EP disclosed
EP-2978749-A1 OPTIONALLY PROTECTED IRIDOID-DERIVED COMPOUNDS, COMPOSITION INCLUDING SAME, USE AS A DYE FOR KERATIN FIBRES AND DEVICES L'Oréal (FR) 2016-02-03 EP disclosed
EP-2978767-A1 DYEING METHOD USING A HAIR-DYEING PRECURSOR OBTAINED FROM IRIDOIDS, COMPOSITION, PRECURSOR AND DEVICE INCLUDING SAME L'OREAL (FR) 2016-02-03 EP disclosed
WO-2014155016-A1 OPTIONALLY PROTECTED IRIDOID-DERIVED COMPOUNDS, COMPOSITION INCLUDING SAME, USE AS A DYE FOR KERATIN FIBRES AND DEVICES L'OREAL (FR) 2014-10-02 WO disclosed
WO-2014154957-A1 DYEING METHOD USING A HAIR-DYEING PRECURSOR OBTAINED FROM IRIDOIDS, COMPOSITION, PRECURSOR AND DEVICE INCLUDING SAME L'OREAL (FR) 2014-10-02 WO disclosed
WO-2011117553-A1 DYEING METHOD USING NON-GLYCOSYLATED IRIDOID DYES, DYEING COMPOSITION AND USE THEREOF L'OREAL (FR) 2011-09-29 WO disclosed
WO-2011117554-A1 DYEING METHOD USING A GLYCOSYLATED IRIDOID DERIVATIVE L'OREAL (FR) 2011-09-29 WO disclosed
CN-1902191-A Amidopyrazole derivative DAIICHI SEIYAKU CO (JP) 2007-01-24 CN disclosed