Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346543 | 0.95 | SRD5A2 (0.70) | SRD5A2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7271917 | 0.85 | SRD5A2 (0.60) | SRD5A2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9422050 | 0.84 | RAB9A (0.56) | SRD5A2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9422052 | 0.84 | RAB9A (0.56) | SRD5A2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9496067 | 0.84 | SRD5A2 (0.79) | SRD5A2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9422061 | 0.83 | CES2 (0.55) | SRD5A2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4342906 | 0.81 | MAPT (0.53) | SRD5A2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9151166 | 0.80 | SRD5A2 (0.59) | SRD5A2MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9648043 | 0.80 | CES2 (0.67) | SRD5A2MAPTRAB9ASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL9148032 | 0.80 | SRD5A2 (0.55) | SRD5A2MAPTRAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464465-B1 | Substituted aminoalkylbiphenyl derivatives, antimycotic composition containing them, and intermediates for their preparation | HOFFMANN LA ROCHE (CH) | 1995-01-11 | — | — | EP | disclosed |
| US-5239084-A | Chmical intermeidates for fungicides, mycosis | HOFFMANN-LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |
| US-5177067-A | Fungicides | HOFFMANN-LAROCHE INC. (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0464465-A1 | Substituted aminoalkylbiphenyl derivatives, antimycotic composition containing them, and intermediates for their preparation | F. HOFFMANN-LA ROCHE AG (CH) | 1992-01-08 | — | — | EP | disclosed |