Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150787 | 0.77 | LTB4R (0.72) | LTB4RALDH1A1KDM4EHSD17B10NOD2 | |
| SCHEMBL27313858 | 0.75 | ACSL1 (0.54) | LTB4RALDH1A1KDM4ENPSR1HSD17B10 | |
| SCHEMBL9149520 | 0.74 | LTB4R (1.00) | LTB4RNPSR1LTB4R2 | |
| SCHEMBL9151106 | 0.73 | LTB4R (0.46) | LTB4RALDH1A1KDM4ENPSR1HSD17B10 | |
| SCHEMBL9150034 | 0.73 | LTB4R (0.49) | LTB4RALDH1A1KDM4ENPSR1HSD17B10 | |
| SCHEMBL9261572 | 0.69 | TSHR (0.62) | ALDH1A1KDM4ENPSR1HSD17B10MAPT | |
| SCHEMBL8878647 | 0.69 | ALDH1A1 (0.69) | ALDH1A1KDM4ENPSR1MAPTMEN1 | |
| SCHEMBL8876847 | 0.68 | CLEC4M (0.47) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL27318901 | 0.68 | KDM4E (0.60) | LTB4RALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL8875460 | 0.68 | ALDH1A1 (0.67) | ALDH1A1KDM4ENPSR1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442748-B1 | Improvements in and relating to leukotriene antagonists | LILLY CO ELI (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0442748-A1 | Improvements in and relating to leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1991-08-21 | — | — | EP | disclosed |
| US-4996230-A | Antiallergens, antiinflammatory agent | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |