Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9149520 | 0.84 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9147969 | 0.83 | LTB4R (0.72) | LTB4RKDM4EFPR1ALDH1A1HPGD | |
| SCHEMBL9150020 | 0.83 | LTB4R (0.71) | LTB4RKDM4EALDH1A1HPGDLTB4R2 | |
| SCHEMBL9152095 | 0.77 | LTB4R (0.58) | LTB4RKDM4ENOD2ALDH1A1HPGD | |
| SCHEMBL9150792 | 0.75 | LTB4R (0.45) | LTB4RKDM4ENOD2ALDH1A1RAB9A | |
| SCHEMBL9150895 | 0.75 | LTB4R (0.73) | LTB4RKDM4EALDH1A1HPGDLTB4R2 | |
| SCHEMBL9154604 | 0.73 | LTB4R (0.53) | LTB4RKDM4EFPR1ALDH1A1HPGD | |
| SCHEMBL9147877 | 0.72 | TSHR (0.45) | ALDH1A1 | |
| SCHEMBL9150025 | 0.71 | LTB4R (0.44) | LTB4RKDM4ENOD2ALDH1A1RAB9A | |
| SCHEMBL9617084 | 0.71 | LTB4R (0.69) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442748-B1 | Improvements in and relating to leukotriene antagonists | LILLY CO ELI (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0442748-A1 | Improvements in and relating to leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1991-08-21 | — | — | EP | disclosed |
| US-4996230-A | Antiallergens, antiinflammatory agent | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |