Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27052933 | 0.92 | EPHX2 (0.41) | LMNAL3MBTL1 | |
| SCHEMBL2231232 | 0.88 | DGKA (0.35) | TSHRALDH1A1KMT2A | |
| SCHEMBL5597403 | 0.87 | ALDH1A1 (0.39) | TSHRLMNAALDH1A1PPARGKMT2A | |
| SCHEMBL16328978 | 0.87 | — | — | |
| SCHEMBL1501122 | 0.87 | ALDH1A1 (0.39) | TSHRLMNAALDH1A1PPARGKMT2A | |
| SCHEMBL13073086 | 0.86 | MCL1 (0.32) | — | |
| SCHEMBL13675273 | 0.85 | — | — | |
| SCHEMBL14570439 | 0.84 | DGKA (0.40) | TSHRLMNAALDH1A1 | |
| SCHEMBL12730964 | 0.84 | — | — | |
| SCHEMBL23735618 | 0.83 | GAA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391723-A | Oligonucleotide conjugates | NEORX CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |