Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.33 |
| ▸ | HMGCR | P04035 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 6/20 | 0.32 |
| ▸ | PPARD | Q03181 | 6/20 | 0.32 |
| ▸ | PPARA | Q07869 | 6/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1501122 | 1.00 | ALDH1A1 (0.39) | ALDH1A1PTPN7HMGCRHSD17B10CYP1A2 | |
| SCHEMBL16328978 | 0.89 | — | — | |
| SCHEMBL14559278 | 0.89 | — | — | |
| SCHEMBL13675273 | 0.88 | — | — | |
| SCHEMBL9152252 | 0.87 | TSHR (0.35) | ALDH1A1TSHRLMNAPPARGKMT2A | |
| SCHEMBL13073086 | 0.86 | MCL1 (0.32) | — | |
| SCHEMBL2231232 | 0.85 | DGKA (0.35) | ALDH1A1HSD17B10CYP1A2MAPTTSHR | |
| SCHEMBL16938606 | 0.83 | — | — | |
| SCHEMBL13060113 | 0.83 | — | — | |
| SCHEMBL22968334 | 0.82 | L3MBTL1 (0.40) | ALDH1A1MAPTTSHRLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257695-B1 | BIOMOLECULES HAVING MULTIPLE ATTACHMENT MOIETIES FOR BINDING TO A SUBSTRATE SURFACE | NANOGEN RECOGNOMICS GMBH (DE) | 2007-03-07 | — | — | EP | claimed |