Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4842155 | 0.85 | HPGD (0.45) | HPGDALDH1A1MTORRAB9AGRM7 | |
| SCHEMBL31248153 | 0.77 | LMNA (0.61) | HPGDALDH1A1CYP3A4ALOX15LMNA | |
| SCHEMBL8268348 | 0.77 | LMNA (0.61) | HPGDALDH1A1CYP3A4ALOX15LMNA | |
| SCHEMBL9156237 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MTORRAB9AGRM7CYP3A4 | |
| SCHEMBL9728882 | 0.71 | HPGD (0.49) | HPGDALDH1A1CYP3A4TSHRALOX15 | |
| SCHEMBL10523666 | 0.71 | CYP2D6 (0.53) | HPGDALDH1A1CYP3A4TSHRALOX15 | |
| SCHEMBL1138843 | 0.69 | HPGD (0.57) | HPGDALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL6895074 | 0.67 | HPGD (0.44) | HPGDALDH1A1LMNAMAPTPKM | |
| SCHEMBL15728805 | 0.67 | MEN1 (0.52) | HPGDALDH1A1RAB9AADRB2HTT | |
| SCHEMBL13975117 | 0.67 | MEN1 (0.52) | HPGDALDH1A1RAB9AADRB2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284621-B1 | NEW PSYCHOSTIMULANT AGENT | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1995-01-18 | — | — | EP | disclosed |
| US-5220068-A | N-propyl-1-phenyl-2-alkylamines | CHINOIN GYOGYSZER - ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1993-06-15 | — | — | US | disclosed |
| US-5075338-A | Using aryl secondary amine | CHINOIN GYOGYSZER- ES VERGYESZETI TERMEKEK GYARA RT. (HU) | 1991-12-24 | — | — | US | disclosed |
| EP-0284621-A1 | NEW PSYCHOSTIMULANT AGENT. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1988-10-05 | — | — | EP | disclosed |
| WO-1988002254-A1 | NEW PSYCHOSTIMULANT AGENT | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1988-04-07 | — | — | WO | disclosed |