SCHEMBL9728882

SCHEMBL9728882

COCCNC(c1ccccc1)C(O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.49
AOC3 Q16853 2/20 0.49
ALDH1A1 P00352 5/20 0.45
MAN2A1 Q16706 2/20 0.43
MAN1B1 Q9UKM7 2/20 0.43
GAA P10253 1/20 0.41
MAPK1 P28482 1/20 0.41
ADRA2C P18825 2/20 0.41
CHRM2 P08172 1/20 0.41
ADRA1A P35348 1/20 0.41
RGS12 O14924 1/20 0.41
GLA P06280 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
PKM P14618 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
ALOX12 P18054 1/20 0.41
NFKB1 P19838 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9729078 0.84 ALDH1A1 (0.47) AOC3ALDH1A1MAN2A1MAN1B1ADRA2C
SCHEMBL10523666 0.83 CYP2D6 (0.53) HPGDALDH1A1MAPK1ADRA2CCHRM2
SCHEMBL6895074 0.81 HPGD (0.44) HPGDAOC3ALDH1A1ADRA2CPKM
SCHEMBL4083083 0.81 AOC3 (0.53) AOC3ALDH1A1MAN2A1MAN1B1ADRA2C
SCHEMBL9729227 0.79 AOC3 (0.55) AOC3ALDH1A1MAN2A1MAN1B1ADRA2C
SCHEMBL9729958 0.78 ALDH1A1 (0.59) AOC3ALDH1A1GAAMAPK1ADRA2C
SCHEMBL9728860 0.78 AOC3 (0.50) AOC3ALDH1A1MAN2A1MAN1B1MAPK1
SCHEMBL9729435 0.77 AOC3 (0.53) AOC3ALDH1A1MAN2A1MAN1B1MAPK1
SCHEMBL11879421 0.77 AOC3 (0.58) AOC3ALDH1A1MAN2A1MAN1B1ADRA2C
SCHEMBL9729205 0.77 ALDH1A1 (0.46) HPGDAOC3ALDH1A1MAN2A1MAN1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4803200-A SHIPPING FEVER SYNDROME A. H. ROBINS COMPANY, INCORPORATED (US) 1989-02-07 US claimed
US-5171753-A Derivatives of 2-amino-1-phenylethanol having antiulcer activity A. H. ROBINS COMPANY, INCORPORATED (US) 1992-12-15 US disclosed
US-4803200-A SHIPPING FEVER SYNDROME A. H. ROBINS COMPANY, INCORPORATED (US) 1989-02-07 US disclosed