Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | CCR6 | P51684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10704901 | 0.85 | MGLL (0.55) | MGLLALDH1A1NPSR1HSP90AA1TLR9 | |
| SCHEMBL11610302 | 0.81 | NPSR1 (0.45) | ALDH1A1NPSR1MEN1KMT2AHCAR1 | |
| SCHEMBL7607085 | 0.80 | MGLL (0.59) | MGLLALDH1A1NPSR1HSP90AA1TLR9 | |
| SCHEMBL9155405 | 0.80 | MGLL (0.59) | MGLLALDH1A1NPSR1HSP90AA1TLR9 | |
| SCHEMBL94095 | 0.78 | MGLL (0.57) | MGLLNPSR1HSP90AA1TLR9PKM | |
| SCHEMBL9418756 | 0.77 | MGLL (0.58) | MGLLALDH1A1NPSR1HSP90AA1TLR9 | |
| SCHEMBL9154820 | 0.77 | ALDH1A1 (0.63) | MGLLALDH1A1NPSR1HSP90AA1TLR9 | |
| SCHEMBL5075617 | 0.76 | MGLL (0.59) | MGLLALDH1A1NPSR1HSP90AA1TLR9 | |
| SCHEMBL8973467 | 0.76 | MGLL (0.53) | MGLLALDH1A1NPSR1HSP90AA1TLR9 | |
| SCHEMBL5078134 | 0.74 | MGLL (0.56) | MGLLALDH1A1NPSR1HSP90AA1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4525864-A2 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MANAGING SICKLE CELL DISEASE AND CONDITIONS RELATED THERETO | Emory University (US) | 2025-03-26 | — | — | EP | claimed |
| WO-2023225300-A2 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MANAGING SICKLE CELL DISEASE AND CONDITIONS RELATED THERETO | EMORY UNIVERSITY (US) | 2023-11-23 | — | — | WO | claimed |
| US-20250361243-A1 | Compounds and Pharmaceutical Compositions Useful for Managing Sickle Cell Disease and Conditions Related Thereto | UNIV EMORY (US) | 2025-11-27 | — | — | US | disclosed |
| EP-4525864-A2 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MANAGING SICKLE CELL DISEASE AND CONDITIONS RELATED THERETO | Emory University (US) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023225300-A2 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MANAGING SICKLE CELL DISEASE AND CONDITIONS RELATED THERETO | EMORY UNIVERSITY (US) | 2023-11-23 | — | — | WO | disclosed |
| EP-0303782-B1 | Resin Composition | SUMITOMO DOW LTD (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0267574-B1 | HEAT RESISTANT COPOLYMER COMPOSITION | Sumitomo Dow Limited (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-4877833-A | BLEND OF POLYMERS OF SPECIFIC COMPOSITION | SUMITOMO NAUGATUCK CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| EP-0303782-A2 | Resin Composition | Sumitomo Dow Limited (JP) | 1989-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250361243-A1 | Compounds and Pharmaceutical Compositions Useful for Managing Sickle Cell Disease and Conditions Related Thereto | THPO, HBG1, HBG2 | MGLL 4083/4885ALDH1A1 84/4885NPSR1 4233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.