Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154092 | 0.92 | RXRB (0.47) | MCL1KMT2AKDM4EGFERRXFP1 | |
| SCHEMBL15936062 | 0.86 | ESR2 (0.56) | KMT2APTGER4 | |
| SCHEMBL4365448 | 0.82 | RXRB (0.53) | MCL1RXRBRXRAALDH1A1ALOX15 | |
| SCHEMBL1311663 | 0.82 | MEN1 (0.53) | KMT2AMEN1ALDH1A1ALOX15TSHR | |
| SCHEMBL18861032 | 0.80 | CA12 (0.43) | KMT2AGFERMEN1ALDH1A1ALOX15 | |
| SCHEMBL874097 | 0.80 | ALDH1A1 (0.47) | KDM4EALDH1A1CYP3A4TSHR | |
| SCHEMBL1375362 | 0.80 | HDAC8 (0.41) | KMT2AMEN1ALDH1A1ALOX15HSD17B1 | |
| SCHEMBL70164 | 0.79 | MCL1 (0.66) | MCL1KMT2AKDM4EGFERRXFP1 | |
| SCHEMBL18431 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1ALOX15CYP3A4 | |
| SCHEMBL1364589 | 0.78 | CES2 (0.47) | KMT2AMEN1ALDH1A1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439616-B1 | METHOD OF PRODUCING 3,4,3',4'-SUBSTITUTED BIPHENYL COMPOUNDS | UBE INDUSTRIES (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5243067-A | Oxidative coupling | UBE INDUSTRIES, LTD. (JP) | 1993-09-07 | — | — | US | disclosed |
| EP-0439616-A1 | METHOD OF PRODUCING 3,4,3',4'-SUBSTITUTED BIPHENYL COMPOUNDS | UBE INDUSTRIES, LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |