SCHEMBL915309

SCHEMBL915309

CC(O)COCCOCCOCCOCCOCCO

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.58
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
TSHR P16473 3/20 0.50
MAPK1 P28482 2/20 0.50
TDP1 Q9NUW8 2/20 0.43
THRB P10828 1/20 0.43
HTT P42858 1/20 0.43
MAPT P10636 1/20 0.43
ALDH1A1 P00352 1/20 0.42
USP2 O75604 1/20 0.33
ADRB2 P07550 2/20 0.32
ADRB1 P08588 2/20 0.32
FYN P06241 1/20 0.32
MAOA P21397 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
SLC6A3 Q01959 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11592794 1.00 HSD17B10 (0.58) HSD17B10MEN1KMT2ATSHRMAPK1
SCHEMBL946410 1.00 HSD17B10 (0.58) HSD17B10MEN1KMT2ATSHRMAPK1
SCHEMBL1434303 1.00 HSD17B10 (0.58) HSD17B10MEN1KMT2ATSHRMAPK1
SCHEMBL917170 1.00 HSD17B10 (0.58) HSD17B10MEN1KMT2ATSHRMAPK1
SCHEMBL16445915 1.00 HSD17B10 (0.58) HSD17B10MEN1KMT2ATSHRMAPK1
Ammonia Solution, Strong SCHEMBL2961801 0.98 HSD17B10 (0.56) HSD17B10MEN1KMT2ATSHRMAPK1
Ammonia Solution, Strong SCHEMBL2955800 0.98 HSD17B10 (0.56) HSD17B10MEN1KMT2ATSHRMAPK1
Hydrochloric Acid SCHEMBL5860540 0.98 HSD17B10 (0.56) HSD17B10MEN1KMT2ATSHRMAPK1
SCHEMBL22497668 0.95
SCHEMBL1071881 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105801686-B Insulin-oligomer conjugates, formulations and uses thereof 比奥孔有限公司 2020-04-07 CN disclosed
CN-105637075-B Novel functional fluid compositions 巴斯夫欧洲公司 2019-01-04 CN disclosed
CN-104302747-B Novel low viscosity functional fluid compositions 巴斯夫欧洲公司 2016-12-28 CN disclosed
EP-2626368-B1 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LTD (IN) 2016-12-21 EP disclosed
CN-105637075-A Novel functional fluid compositions BASF SE 2016-06-01 CN disclosed
US-9101596-B2 Cation complexes of insulin compound conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9102758-B2 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
EP-1773878-B1 INSULIN-OLIGOMER CONJUGATES, FORMULATIONS AND USES THEREOF BIOCON LTD (IN) 2015-03-04 EP disclosed
CN-104302747-A Novel low viscosity functional fluid compositions BASF SE 2015-01-21 CN disclosed
US-8563685-B2 Fatty acid formulations and oral delivery of proteins and peptides, and uses thereof BIOCON LIMITED (IN) 2013-10-22 US disclosed
US-20110118179-A1 CATION COMPLEXES OF INSULIN COMPOUND CONJUGATES, FORMULATIONS AND USES THEREOF RADHAKRISHNAN BALASINGAM 2011-05-19 US disclosed
US-7875700-B2 polyoxyethylene glycol moieties; crystalline solid or a rod shaped crystal; proinsulin; pharmacokinetics; treating diabetes BIOCON LIMITED (IN) 2011-01-25 US disclosed
US-7872095-B2 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2011-01-18 US disclosed
US-20100105605-A1 FATTY ACID FORMULATIONS AND ORAL DELIVERY OF PROTEINS AND PEPTIDES, AND USES THEREOF RADHAKRISHNAN BALASINGAM 2010-04-29 US disclosed
US-7605123-B2 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof BIOCON LTD. (IN) 2009-10-20 US disclosed
EP-1773878-A2 INSULIN-OLIGOMER CONJUGATES, FORMULATIONS AND USES THEREOF Nobex Corporation (US) 2007-04-18 EP disclosed
WO-2006014673-A2 INSULIN-OLIGOMER CONJUGATES, FORMULATIONS AND USES THEREOF NOBEX CORPORATION (US) 2006-02-09 WO disclosed
US-20060018874-A1 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof BIOCON LIMITED (IN) 2006-01-26 US disclosed
US-20060019873-A1 Cation complexes of insulin compound conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2006-01-26 US disclosed
US-20060019874-A1 Cation complexes of insulin compund conjugates, formulation and uses thereof NOBEX CORPORATION 2006-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060019873-A1 Cation complexes of insulin compound conjugates, formulations and uses thereof GPR119, INSR, IAPP HSD17B10 1399/4885MEN1 524/4885KMT2A 3285/4885
US-20100105605-A1 FATTY ACID FORMULATIONS AND ORAL DELIVERY OF PROTEINS AND PEPTIDES, AND USES THEREOF FABP2, SLC27A1, SLC27A2 HSD17B10 1585/4885MEN1 1673/4885KMT2A 4516/4885
US-20060018874-A1 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof FABP2, SLC27A1, SLC27A2 HSD17B10 1557/4885MEN1 1710/4885KMT2A 4506/4885
US-20110118179-A1 CATION COMPLEXES OF INSULIN COMPOUND CONJUGATES, FORMULATIONS AND USES THEREOF GPR119, INSR, IAPP HSD17B10 1501/4885MEN1 536/4885KMT2A 3472/4885
US-20060019874-A1 Cation complexes of insulin compund conjugates, formulation and uses thereof INSR, GPR119, IAPP HSD17B10 461/4885MEN1 203/4885KMT2A 2500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.