Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 5/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154812 | 0.87 | NOTUM (0.39) | CTSVCTSLCTSSCTSKMAPT | |
| SCHEMBL7400371 | 0.77 | CYP2C9 (0.43) | MAPTMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL9154694 | 0.76 | PYGM (0.46) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6951541 | 0.69 | LMNA (0.36) | ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL4732866 | 0.68 | NR3C2 (0.33) | ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL16572042 | 0.66 | MYC (0.61) | MAPK14MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL4755356 | 0.66 | TSHR (0.37) | MAPTKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL9153388 | 0.65 | PYGM (0.36) | CTSAMAPTLMNAFGFR3KDR | |
| SCHEMBL12896087 | 0.65 | PIM1 (0.52) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL38650804 | 0.63 | CTSA (0.51) | CTSAMAPTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403849-A | Treatment of central nervous system disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-04 | — | — | US | claimed |