Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949740 | 0.84 | PRMT1 (0.50) | CYP2D6 | |
| Hydrochloric Acid SCHEMBL7083326 | 0.82 | PRSS1 (0.51) | CYP2D6 | |
| Hydrochloric Acid SCHEMBL6949761 | 0.82 | PRSS1 (0.51) | CYP2D6 | |
| SCHEMBL9578575 | 0.79 | MAPT (0.69) | MAPTTP53TSHRPLA2G4B | |
| SCHEMBL6946501 | 0.79 | MAPT (0.69) | MAPTTP53TSHRPLA2G4B | |
| SCHEMBL14125959 | 0.79 | MAPT (0.69) | MAPTTP53TSHRPLA2G4B | |
| SCHEMBL4276906 | 0.79 | MAPT (0.69) | MAPTTP53TSHRPLA2G4B | |
| SCHEMBL7548158 | 0.79 | MAPT (0.69) | MAPTTP53TSHRPLA2G4B | |
| SCHEMBL7555804 | 0.78 | MAPT (0.50) | MAPTCYP3A4CYP2D6SMPD1TP53 | |
| SCHEMBL6953681 | 0.78 | NNMT (0.59) | MAPTCYP3A4TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5443754-A | Pyridylpyrimidines, a process for their preparation and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-22 | — | — | US | disclosed |