Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160859 | 0.85 | HPGD (0.55) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL9471748 | 0.85 | SMN1; SMN2 (0.46) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL9158344 | 0.85 | PLA2G1B (0.43) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL9152726 | 0.84 | SMN1; SMN2 (0.44) | ALDH1A1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL9158537 | 0.82 | CACNA2D1 (0.40) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL9152715 | 0.82 | CACNA2D1 (0.41) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL9153694 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL9152163 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL9152169 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL9157264 | 0.79 | HPGD (0.46) | ALDH1A1KMT2AMEN1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |