Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156791 | 0.85 | RIPK1 (0.44) | OPRD1 | |
| SCHEMBL9152169 | 0.84 | ALDH1A1 (0.53) | HPGDSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL9152163 | 0.84 | ALDH1A1 (0.53) | HPGDSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL9152133 | 0.83 | NPC1 (0.47) | RAB9ASMN1; SMN2KMT2AMEN1OPRD1 | |
| SCHEMBL9157008 | 0.82 | RAB9A (0.53) | HPGDRAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11413247 | 0.81 | HPGD (0.46) | HPGDRAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9158254 | 0.81 | RIPK1 (0.48) | — | |
| SCHEMBL9155537 | 0.81 | OPRM1 (0.36) | OPRD1 | |
| SCHEMBL9471748 | 0.79 | SMN1; SMN2 (0.46) | HPGDRAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9154036 | 0.79 | ALDH1A1 (0.50) | HPGDRAB9ASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |