Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152163 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HPGDGLAKMT2AMEN1 | |
| SCHEMBL9157264 | 0.84 | HPGD (0.46) | ALDH1A1HPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9157344 | 0.81 | L3MBTL1 (0.59) | ALDH1A1HPGDGLAKMT2AMEN1 | |
| SCHEMBL9157351 | 0.81 | L3MBTL1 (0.59) | ALDH1A1HPGDGLAKMT2AMEN1 | |
| SCHEMBL9154036 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9160859 | 0.78 | HPGD (0.55) | ALDH1A1HPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9158344 | 0.77 | PLA2G1B (0.43) | ALDH1A1HPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9471748 | 0.77 | SMN1; SMN2 (0.46) | ALDH1A1HPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9155537 | 0.76 | OPRM1 (0.36) | PKMOPRD1 | |
| SCHEMBL9152726 | 0.76 | SMN1; SMN2 (0.44) | ALDH1A1HPGDKMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |