Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265384 | 0.86 | HPGD (0.38) | EPHX1CTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL6799750 | 0.81 | EPHX1 (0.63) | EPHX1CTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL60318 | 0.79 | EPHX1 (0.56) | EPHX1CTSSCTSKKMT2AGAA | |
| SCHEMBL4635466 | 0.79 | EPHX1 (0.50) | EPHX1CTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL7279909 | 0.78 | HPGD (0.51) | EPHX1CTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL4073139 | 0.78 | EPHX1 (0.60) | EPHX1CTSSCTSKKMT2AGAA | |
| SCHEMBL24938547 | 0.78 | KMT2A (0.45) | EPHX1CTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL10209101 | 0.77 | EPHX1 (0.54) | EPHX1CTSSCTSKKMT2AGAA | |
| SCHEMBL4072834 | 0.76 | EPHX1 (0.57) | EPHX1CTSSCTSKKMT2AALDH1A1 | |
| Bicarbonate SCHEMBL5780143 | 0.76 | EPHX1 (0.54) | EPHX1CTSSCTSKKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036051-A | Renin inhibitors | ABBOTT LABORATORIES (US) | 1991-07-30 | — | — | US | disclosed |