Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 6/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 5/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154611 | 1.00 | LTB4R (0.53) | LTB4RLTB4R2DRD3KDM4EALDH1A1 | |
| SCHEMBL9150347 | 0.81 | LTB4R (0.76) | LTB4RLTB4R2DRD3KDM4EALDH1A1 | |
| SCHEMBL9150787 | 0.73 | LTB4R (0.72) | LTB4RLTB4R2KDM4EALDH1A1GAA | |
| SCHEMBL9218820 | 0.72 | LTB4R (0.65) | LTB4RLTB4R2DRD3ALDH1A1GAA | |
| SCHEMBL9427079 | 0.72 | LTB4R (0.65) | LTB4RLTB4R2DRD3ALDH1A1GAA | |
| SCHEMBL9445158 | 0.71 | LTB4R (0.58) | LTB4RLTB4R2DRD3KDM4EALDH1A1 | |
| SCHEMBL9697914 | 0.71 | LTB4R (0.58) | LTB4RLTB4R2DRD3ALDH1A1MAPT | |
| SCHEMBL9445156 | 0.71 | LTB4R (0.58) | LTB4RLTB4R2DRD3KDM4EALDH1A1 | |
| SCHEMBL9697919 | 0.71 | LTB4R (0.58) | LTB4RLTB4R2DRD3ALDH1A1MAPT | |
| SCHEMBL9445356 | 0.70 | LTB4R (0.56) | LTB4RLTB4R2DRD3ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442748-B1 | Improvements in and relating to leukotriene antagonists | LILLY CO ELI (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0442748-A1 | Improvements in and relating to leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1991-08-21 | — | — | EP | disclosed |
| US-4996230-A | Antiallergens, antiinflammatory agent | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |